RETROSPECTIVE ANALYSIS OF OPERATIVE MATERIALS OF PATIENTS OF REPRODUCTIVE PERIOD WITH LEIOMYOMA

Leiomyoma is a benign tumor of unknown etiology the uterus. stimulated by an excess steroids, disruption apoptotic mechanisms, and local growth factors.We conducted retrospective analysis operative material with leiomyoma reproductive period women uterine body. The study revealed: sharp increase in incidence intramural leiomyoma; Histological structural features are characteristic proliferative, recurrent, latent leiomyomas; Active products extracellular matrix, which important not only terms growth, but it likely to be among factors that limit free uncontrolled spread proliferate body muscle inhibit assimilation process; Retrospective provides basis for search molecular mechanisms development. results obtained will selection drug treatment (in inhibition myocyte proliferative processes, expression activation apoptosis).